abnormal mandibular coronoid process morphology_Bmp4<tm2(tetO-Bmp4,lacZ)Jfm>/Bmp4<+>,Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0

http://metadb.riken.jp/0004594I129SvC57BL6JCBAJBmp4tm2tetOBmp4lacZJfmBmp4GtROSA26Sortm1rtTAEGFPNagyGtROSA26SorTgWnt1cre11Rth0Bmp4tm2tetOBmp4lacZJfmGtROSA26SorTgWnt1cre11RthBmp4GtROSA26Sortm1rtTAEGFPNagy

abnormal mandibular coronoid process morphology_Bmp4<tm2(tetO-Bmp4,lacZ)Jfm>/Bmp4<+>,Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 11, David H Rowitch
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447280
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• bone morphogenetic protein 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:88180

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Bmp4<tm2(tetO-Bmp4,lacZ)Jfm>/Bmp4<+>,Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Bmp4<tm2(tetO-Bmp4,lacZ)Jfm>|Gt(ROSA)26Sor<+>|Tg(Wnt1-cre)11Rth|Bmp4<+>|Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6J * CBA/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal mandibular coronoid process morphology
  http://purl.obolibrary.org/obo/MP_0004594

文献

http://purl.org/net/cito/citesAsAuthority

• Margarita. Bonilla-Claudio, et.al., Bmp signaling regulates a dose-dependent transcriptional program to control facial skeletal development., Development (Cambridge, England), 2012, 139
  http://rdf.ncbi.nlm.nih.gov/pubmed/22219353