decreased length of long bones_Hif1a<tm1Rsjo>/Hif1a<tm3Rsjo>,Tg(Col2a1-cre)1Rsjo/?

http://metadb.riken.jp/0004686I129S1Sv129X1SvJFVBNHif1atm1RsjoHif1atm3RsjoTgCol2a1cre1RsjoTgCol2a1cre1RsjoHif1atm1RsjoHif1atm3Rsjo

decreased length of long bones_Hif1a<tm1Rsjo>/Hif1a<tm3Rsjo>,Tg(Col2a1-cre)1Rsjo/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Randall S Johnson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2450251
• hypoxia inducible factor 1, alpha subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:106918

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hif1a<tm1Rsjo>/Hif1a<tm3Rsjo>,Tg(Col2a1-cre)1Rsjo/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Col2a1-cre)1Rsjo|Hif1a<tm1Rsjo>|Hif1a<tm3Rsjo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased length of long bones
  http://purl.obolibrary.org/obo/MP_0004686

文献

http://purl.org/net/cito/citesAsAuthority

• E. Schipani, et.al., Hypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth arrest and survival., Genes & development, 2001, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/11691837