decreased circulating insulin-like growth factor I level_Sirt1<tm3Fwa>/Sirt1<tm3Fwa>,Tg(Nes-cre)1Kln/0

http://metadb.riken.jp/0004701I129S6SvEvTacC57BL6SJLSirt1tm3FwaSirt1tm3FwaTgNescre1Kln0TgNescre1KlnSirt1tm3Fwa

decreased circulating insulin-like growth factor I level_Sirt1<tm3Fwa>/Sirt1<tm3Fwa>,Tg(Nes-cre)1Kln/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• sirtuin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:2135607
• transgene insertion 1, Rudiger Klein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176172

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sirt1<tm3Fwa>/Sirt1<tm3Fwa>,Tg(Nes-cre)1Kln/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Nes-cre)1Kln|Sirt1<tm3Fwa>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased circulating insulin-like growth factor I level
  http://purl.obolibrary.org/obo/MP_0004701

文献

http://purl.org/net/cito/citesAsAuthority

• Dena E. Cohen, et.al., Neuronal SIRT1 regulates endocrine and behavioral responses to calorie restriction., Genes & development, 2009, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/20008932