decreased circulating insulin-like growth factor I level_Igf1<tm1Dlr>/Igf1<tm1Dlr>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0004701I129SvC57BL6CBAIgf1tm1DlrIgf1tm1DlrTgMx1cre1Cgn0TgMx1cre1CgnIgf1tm1Dlr

decreased circulating insulin-like growth factor I level_Igf1<tm1Dlr>/Igf1<tm1Dlr>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• insulin-like growth factor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:96432
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Igf1<tm1Dlr>/Igf1<tm1Dlr>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Mx1-cre)1Cgn|Igf1<tm1Dlr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased circulating insulin-like growth factor I level
  http://purl.obolibrary.org/obo/MP_0004701

文献

http://purl.org/net/cito/citesAsAuthority

• Johan. Svensson, et.al., Liver-derived IGF-I regulates kidney size, sodium reabsorption, and renal IGF-II expression., The Journal of endocrinology, 2007, 193
  http://rdf.ncbi.nlm.nih.gov/pubmed/17535874
• K. Sjögren, et.al., Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice., Proceedings of the National Academy of Sciences of the United States of America, 1999, 96
  http://rdf.ncbi.nlm.nih.gov/pubmed/10359843