increased susceptibility to age-related hearing loss_Fscn2<ahl8>/Fscn2<ahl8>

http://metadb.riken.jp/0004748DBA2JFscn2ahl8Fscn2ahl8Fscn2ahl8

increased susceptibility to age-related hearing loss_Fscn2<ahl8>/Fscn2<ahl8>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• fascin actin-bundling protein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:2443337

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fscn2<ahl8>/Fscn2<ahl8>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Fscn2<ahl8>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• DBA/2J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to age-related hearing loss
  http://purl.obolibrary.org/obo/MP_0004748

文献

http://purl.org/net/cito/citesAsAuthority

• Kenneth R. Johnson, et.al., A locus on distal chromosome 11 (ahl8) and its interaction with Cdh23 ahl underlie the early onset, age-related hearing loss of DBA/2J mice., Genomics, 2008, 92
  http://rdf.ncbi.nlm.nih.gov/pubmed/18662770
• Jung-Bum. Shin, et.al., The R109H variant of fascin-2, a developmentally regulated actin crosslinker in hair-cell stereocilia, underlies early-onset hearing loss of DBA/2J mice., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/20660251