increased susceptibility to age-related hearing loss_Actb<tm1.1Erv>/Actb<tm1.1Erv>,Tg(Atoh1-cre)1Bfri/?

http://metadb.riken.jp/0004748I129S6SvEvTacC57BL6CBAFVBNActbtm11ErvActbtm11ErvTgAtoh1cre1BfriTgAtoh1cre1BfriActbtm11Erv

increased susceptibility to age-related hearing loss_Actb<tm1.1Erv>/Actb<tm1.1Erv>,Tg(Atoh1-cre)1Bfri/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Bernd Fritzsch
  http://metadb.riken.jp/db/mgi_rdf/MGI:3775842
• actin, beta
  http://metadb.riken.jp/db/mgi_rdf/MGI:87904

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Actb<tm1.1Erv>/Actb<tm1.1Erv>,Tg(Atoh1-cre)1Bfri/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Atoh1-cre)1Bfri|Actb<tm1.1Erv>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * CBA * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to age-related hearing loss
  http://purl.obolibrary.org/obo/MP_0004748

文献

http://purl.org/net/cito/citesAsAuthority

• Benjamin J. Perrin, et.al., β-actin and γ-actin are each dispensable for auditory hair cell development but required for Stereocilia maintenance., PLoS genetics, 2010, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/20976199