increased anti-double stranded DNA antibody level_Myd88<tm1Aki>/Myd88<tm1Aki>,Tank<tm1Aki>/Tank<tm1Aki>

http://metadb.riken.jp/0004762I129Sv129P2OlaHsdC57BL6Myd88tm1AkiMyd88tm1AkiTanktm1AkiTanktm1AkiMyd88tm1AkiTanktm1Aki

increased anti-double stranded DNA antibody level_Myd88<tm1Aki>/Myd88<tm1Aki>,Tank<tm1Aki>/Tank<tm1Aki>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• TRAF family member-associated Nf-kappa B activator
  http://metadb.riken.jp/db/mgi_rdf/MGI:107676
• myeloid differentiation primary response gene 88
  http://metadb.riken.jp/db/mgi_rdf/MGI:108005

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Myd88<tm1Aki>/Myd88<tm1Aki>,Tank<tm1Aki>/Tank<tm1Aki>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Myd88<tm1Aki>|Tank<tm1Aki>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased anti-double stranded DNA antibody level
  http://purl.obolibrary.org/obo/MP_0004762

文献

http://purl.org/net/cito/citesAsAuthority

• Tatsukata. Kawagoe, et.al., TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis., Nature immunology, 2009, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/19668221