abnormal bile composition_Cyp27a1<tm1Elt>/Cyp27a1<tm1Elt>

http://metadb.riken.jp/0004773I129SvC57BL6JCyp27a1tm1EltCyp27a1tm1EltCyp27a1tm1Elt

abnormal bile composition_Cyp27a1<tm1Elt>/Cyp27a1<tm1Elt>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cytochrome P450, family 27, subfamily a, polypeptide 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88594

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cyp27a1<tm1Elt>/Cyp27a1<tm1Elt>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cyp27a1<tm1Elt>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal bile composition
  http://purl.obolibrary.org/obo/MP_0004773

文献

http://purl.org/net/cito/citesAsAuthority

• J J. Repa, et.al., Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia. Reversal by cholic acid feeding., The Journal of biological chemistry, 2000, 275
  http://rdf.ncbi.nlm.nih.gov/pubmed/11001949
• H. Rosen, et.al., Markedly reduced bile acid synthesis but maintained levels of cholesterol and vitamin D metabolites in mice with disrupted sterol 27-hydroxylase gene., The Journal of biological chemistry, 1998, 273
  http://rdf.ncbi.nlm.nih.gov/pubmed/9614081