abnormal dorsal aorta morphology_Ccm2<Gt(RRG051)Byg>/Ccm2<+>,Heg1<tm1Mlkn>/Heg1<+>

http://metadb.riken.jp/0004787I129Sv129P2OlaHsdC57BL6Ccm2GtRRG051BygCcm2Heg1tm1MlknHeg1Heg1tm1MlknHeg1Ccm2Ccm2GtRRG051Byg

abnormal dorsal aorta morphology_Ccm2<Gt(RRG051)Byg>/Ccm2<+>,Heg1<tm1Mlkn>/Heg1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• heart development protein with EGF-like domains 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1924696
• cerebral cavernous malformation 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:2384924

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ccm2<Gt(RRG051)Byg>/Ccm2<+>,Heg1<tm1Mlkn>/Heg1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Heg1<tm1Mlkn>|Heg1<+>|Ccm2<+>|Ccm2<Gt(RRG051)Byg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal dorsal aorta morphology
  http://purl.obolibrary.org/obo/MP_0004787

文献

http://purl.org/net/cito/citesAsAuthority

• Benjamin. Kleaveland, et.al., Regulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathway., Nature medicine, 2009, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/19151727