increased susceptibility to experimental autoimmune encephalomyelitis_H2-T23<tm2Cant>/H2-T23<tm2Cant>,Tg(Tcra2D2,Tcrb2D2)1Kuch/?

http://metadb.riken.jp/0004799I129S6SvEvTacH2T23tm2CantH2T23tm2CantTgTcra2D2Tcrb2D21KuchH2T23tm2CantTgTcra2D2Tcrb2D21Kuch

increased susceptibility to experimental autoimmune encephalomyelitis_H2-T23<tm2Cant>/H2-T23<tm2Cant>,Tg(Tcra2D2,Tcrb2D2)1Kuch/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Vijay Kuchroo
  http://metadb.riken.jp/db/mgi_rdf/MGI:3700835
• histocompatibility 2, T region locus 23
  http://metadb.riken.jp/db/mgi_rdf/MGI:95957

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• H2-T23<tm2Cant>/H2-T23<tm2Cant>,Tg(Tcra2D2,Tcrb2D2)1Kuch/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• H2-T23<tm2Cant>|Tg(Tcra2D2,Tcrb2D2)1Kuch

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to experimental autoimmune encephalomyelitis
  http://purl.obolibrary.org/obo/MP_0004799

文献

http://purl.org/net/cito/citesAsAuthority

• Linrong. Lu, et.al., Regulation of CD8+ regulatory T cells: Interruption of the NKG2A-Qa-1 interaction allows robust suppressive activity and resolution of autoimmune disease., Proceedings of the National Academy of Sciences of the United States of America, 2008, 105
  http://rdf.ncbi.nlm.nih.gov/pubmed/19047627