decreased susceptibility to experimental autoimmune encephalomyelitis_Fas<tm1Cgn>/Fas<tm1Cgn>,Mog<tm1(cre)Gkl>/Mog<+>,Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>

http://metadb.riken.jp/0004800I129S2SvPasC57BL6Fastm1CgnFastm1CgnMogtm1creGklMogTnfrsf1atm1MakTnfrsf1atm1MakFastm1CgnMogTnfrsf1atm1MakMogtm1creGkl

decreased susceptibility to experimental autoimmune encephalomyelitis_Fas<tm1Cgn>/Fas<tm1Cgn>,Mog<tm1(cre)Gkl>/Mog<+>,Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Fas (TNF receptor superfamily member 6)
  http://metadb.riken.jp/db/mgi_rdf/MGI:95484
• myelin oligodendrocyte glycoprotein
  http://metadb.riken.jp/db/mgi_rdf/MGI:97435
• tumor necrosis factor receptor superfamily, member 1a
  http://metadb.riken.jp/db/mgi_rdf/MGI:1314884

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fas<tm1Cgn>/Fas<tm1Cgn>,Mog<tm1(cre)Gkl>/Mog<+>,Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Fas<tm1Cgn>|Mog<+>|Tnfrsf1a<tm1Mak>|Mog<tm1(cre)Gkl>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased susceptibility to experimental autoimmune encephalomyelitis
  http://purl.obolibrary.org/obo/MP_0004800

文献

http://purl.org/net/cito/citesAsAuthority

• Nadine. Hövelmeyer, et.al., Apoptosis of oligodendrocytes via Fas and TNF-R1 is a key event in the induction of experimental autoimmune encephalomyelitis., Journal of immunology (Baltimore, Md. : 1950), 2005, 175
  http://rdf.ncbi.nlm.nih.gov/pubmed/16237080