increased susceptibility to autoimmune diabetes_Cd80<tm1Shr>/Cd80<tm1Shr>,Cd86<tm2Shr>/Cd86<tm2Shr>

http://metadb.riken.jp/0004803I129S4SvJaeNODCd80tm1ShrCd80tm1ShrCd86tm2ShrCd86tm2ShrCd86tm2ShrCd80tm1Shr

increased susceptibility to autoimmune diabetes_Cd80<tm1Shr>/Cd80<tm1Shr>,Cd86<tm2Shr>/Cd86<tm2Shr>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• CD86 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:101773
• CD80 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:101775

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd80<tm1Shr>/Cd80<tm1Shr>,Cd86<tm2Shr>/Cd86<tm2Shr>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cd86<tm2Shr>|Cd80<tm1Shr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * NOD

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to autoimmune diabetes
  http://purl.obolibrary.org/obo/MP_0004803

文献

http://purl.org/net/cito/citesAsAuthority

• B. Salomon, et.al., B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes., Immunity, 2000, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/10795741