increased susceptibility to autoimmune diabetes_Cd274<tm1Shr>/Cd274<tm1Shr>,Tg(TcraTcrb)1100Mjb/0

http://metadb.riken.jp/0004803IC57BL6Cd274tm1ShrCd274tm1ShrTgTcraTcrb1100Mjb0TgTcraTcrb1100MjbCd274tm1Shr

increased susceptibility to autoimmune diabetes_Cd274<tm1Shr>/Cd274<tm1Shr>,Tg(TcraTcrb)1100Mjb/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1100, Michael J Bevan
  http://metadb.riken.jp/db/mgi_rdf/MGI:3055219
• CD274 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:1926446

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd274<tm1Shr>/Cd274<tm1Shr>,Tg(TcraTcrb)1100Mjb/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(TcraTcrb)1100Mjb|Cd274<tm1Shr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to autoimmune diabetes
  http://purl.obolibrary.org/obo/MP_0004803

文献

http://purl.org/net/cito/citesAsAuthority

• Mary E. Keir, et.al., PD-1 regulates self-reactive CD8+ T cell responses to antigen in lymph nodes and tissues., Journal of immunology (Baltimore, Md. : 1950), 2007, 179
  http://rdf.ncbi.nlm.nih.gov/pubmed/17911591