increased susceptibility to autoimmune diabetes_B2m<tm1Unc>/B2m<tm1Unc>,Tg(B2M)55Hpl/Tg(B2M)55Hpl,Tg(HLA-A2.1)1Enge/Tg(HLA-A2.1)1Enge

http://metadb.riken.jp/0004803NODCgB2mtm1UncTgB2M55HplTgHLAA211EngeB2mtm1UncB2mtm1UncTgB2M55HplTgB2M55HplTgHLAA211EngeTgHLAA211EngeB2mtm1UncTgHLAA211EngeTgB2M55Hpl

increased susceptibility to autoimmune diabetes_B2m<tm1Unc>/B2m<tm1Unc>,Tg(B2M)55Hpl/Tg(B2M)55Hpl,Tg(HLA-A2.1)1Enge/Tg(HLA-A2.1)1Enge

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 55, Hidde Ploegh
  http://metadb.riken.jp/db/mgi_rdf/MGI:2159099
• beta-2 microglobulin
  http://metadb.riken.jp/db/mgi_rdf/MGI:88127
• transgene insertion 1, Victor H Engelhard
  http://metadb.riken.jp/db/mgi_rdf/MGI:3056376

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• B2m<tm1Unc>/B2m<tm1Unc>,Tg(B2M)55Hpl/Tg(B2M)55Hpl,Tg(HLA-A2.1)1Enge/Tg(HLA-A2.1)1Enge

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• B2m<tm1Unc>|Tg(HLA-A2.1)1Enge|Tg(B2M)55Hpl

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• NOD.Cg-B2m<tm1Unc> Tg(B2M)55Hpl Tg(HLA-A2.1)1Enge

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to autoimmune diabetes
  http://purl.obolibrary.org/obo/MP_0004803

文献

http://purl.org/net/cito/citesAsAuthority

• Michele P. Marron, et.al., Functional evidence for the mediation of diabetogenic T cell responses by HLA-A2.1 MHC class I molecules through transgenic expression in NOD mice., Proceedings of the National Academy of Sciences of the United States of America, 2002, 99
  http://rdf.ncbi.nlm.nih.gov/pubmed/12361980