increased susceptibility to autoimmune diabetes_Fas<tm1Vbo>/Fas<tm1Vbo>,Tg(Ins2-cre)25Mgn/0,Tg(Ins2-HA)165Bri/0,Tg(Tcra/Tcrb)1Vbo/0

http://metadb.riken.jp/0004803NSFastm1VboFastm1VboTgIns2cre25Mgn0TgIns2HA165Bri0TgTcraTcrb1Vbo0TgIns2cre25MgnTgIns2HA165BriTgTcraTcrb1VboFastm1Vbo

increased susceptibility to autoimmune diabetes_Fas<tm1Vbo>/Fas<tm1Vbo>,Tg(Ins2-cre)25Mgn/0,Tg(Ins2-HA)165Bri/0,Tg(Tcra/Tcrb)1Vbo/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Harald von Boehmer
  http://metadb.riken.jp/db/mgi_rdf/MGI:2680177
• transgene insertion 25, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176225
• transgene insertion 165, Ralph Brinster
  http://metadb.riken.jp/db/mgi_rdf/MGI:2680174
• Fas (TNF receptor superfamily member 6)
  http://metadb.riken.jp/db/mgi_rdf/MGI:95484

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fas<tm1Vbo>/Fas<tm1Vbo>,Tg(Ins2-cre)25Mgn/0,Tg(Ins2-HA)165Bri/0,Tg(Tcra/Tcrb)1Vbo/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Ins2-cre)25Mgn|Tg(Ins2-HA)165Bri|Tg(Tcra/Tcrb)1Vbo|Fas<tm1Vbo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• Not Specified

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to autoimmune diabetes
  http://purl.obolibrary.org/obo/MP_0004803

文献

http://purl.org/net/cito/citesAsAuthority

• Irina. Apostolou, et.al., Effective destruction of Fas-deficient insulin-producing beta cells in type 1 diabetes., The Journal of experimental medicine, 2003, 198
  http://rdf.ncbi.nlm.nih.gov/pubmed/14530378