decreased susceptibility to autoimmune diabetes_Stat4<tm1Gru>/Stat4<tm1Gru>,Tg(Ins2-NP)25-3Olds/0

http://metadb.riken.jp/0004804I129S2SvPasBALBcC57BL6Stat4tm1GruStat4tm1GruTgIns2NP253Olds0Stat4tm1GruTgIns2NP253Olds

decreased susceptibility to autoimmune diabetes_Stat4<tm1Gru>/Stat4<tm1Gru>,Tg(Ins2-NP)25-3Olds/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• signal transducer and activator of transcription 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:103062
• transgene insertion 25-3, Michael BA Oldstone, MD
  http://metadb.riken.jp/db/mgi_rdf/MGI:3531505

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Stat4<tm1Gru>/Stat4<tm1Gru>,Tg(Ins2-NP)25-3Olds/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Stat4<tm1Gru>|Tg(Ins2-NP)25-3Olds

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * BALB/c * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased susceptibility to autoimmune diabetes
  http://purl.obolibrary.org/obo/MP_0004804

文献

http://purl.org/net/cito/citesAsAuthority

• A. Holz, et.al., Disruption of the STAT4 signaling pathway protects from autoimmune diabetes while retaining antiviral immune competence., Journal of immunology (Baltimore, Md. : 1950), 1999, 163
  http://rdf.ncbi.nlm.nih.gov/pubmed/10553062