increased hematopoietic stem cell number_Idh1<tm1Mak>/Idh1<tm1Mak>,Tg(Vav1-icre)A2Kio/0

http://metadb.riken.jp/0004809I129P2OlaHsdC57BL6C57BL10CBACaIdh1tm1MakIdh1tm1MakTgVav1icreA2Kio0Idh1tm1MakTgVav1icreA2Kio

increased hematopoietic stem cell number_Idh1<tm1Mak>/Idh1<tm1Mak>,Tg(Vav1-icre)A2Kio/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• isocitrate dehydrogenase 1 (NADP+), soluble
  http://metadb.riken.jp/db/mgi_rdf/MGI:96413
• transgene insertion A2, Dimitris Kioussis
  http://metadb.riken.jp/db/mgi_rdf/MGI:2449945

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Idh1<tm1Mak>/Idh1<tm1Mak>,Tg(Vav1-icre)A2Kio/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Idh1<tm1Mak>|Tg(Vav1-icre)A2Kio

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * C57BL/10 * CBA/Ca

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hematopoietic stem cell number
  http://purl.obolibrary.org/obo/MP_0004809

文献

http://purl.org/net/cito/citesAsAuthority

• Masato. Sasaki, et.al., IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics., Nature, 2012, 488
  http://rdf.ncbi.nlm.nih.gov/pubmed/22763442