increased hematopoietic stem cell number_Idh1<tm1Mak>/Idh1<tm1Mak>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

http://metadb.riken.jp/0004809I129P2OlaHsdC57BL6Idh1tm1MakIdh1tm1MakLyz2tm1creIfoLyz2Idh1tm1MakLyz2Lyz2tm1creIfo

increased hematopoietic stem cell number_Idh1<tm1Mak>/Idh1<tm1Mak>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• lysozyme 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:96897
• isocitrate dehydrogenase 1 (NADP+), soluble
  http://metadb.riken.jp/db/mgi_rdf/MGI:96413

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Idh1<tm1Mak>/Idh1<tm1Mak>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Idh1<tm1Mak>|Lyz2<+>|Lyz2<tm1(cre)Ifo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hematopoietic stem cell number
  http://purl.obolibrary.org/obo/MP_0004809

文献

http://purl.org/net/cito/citesAsAuthority

• Masato. Sasaki, et.al., IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics., Nature, 2012, 488
  http://rdf.ncbi.nlm.nih.gov/pubmed/22763442