increased hematopoietic stem cell number_Etv6<tm1(RUNX1)Haho>/Etv6<+>,Runx1<tm3Spe>/Runx1<+>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0004809I129S1Sv129S4SvJaeC57BL6CBAEtv6tm1RUNX1HahoEtv6Runx1tm3SpeRunx1TgMx1cre1Cgn0Runx1Etv6tm1RUNX1HahoTgMx1cre1CgnRunx1tm3SpeEtv6

increased hematopoietic stem cell number_Etv6<tm1(RUNX1)Haho>/Etv6<+>,Runx1<tm3Spe>/Runx1<+>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• runt related transcription factor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:99852
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072
• ets variant 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:109336

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Etv6<tm1(RUNX1)Haho>/Etv6<+>,Runx1<tm3Spe>/Runx1<+>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Runx1<+>|Etv6<tm1(RUNX1)Haho>|Tg(Mx1-cre)1Cgn|Runx1<tm3Spe>|Etv6<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S4/SvJae * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hematopoietic stem cell number
  http://purl.obolibrary.org/obo/MP_0004809

文献

http://purl.org/net/cito/citesAsAuthority

• Jeffrey W. Schindler, et.al., TEL-AML1 corrupts hematopoietic stem cells to persist in the bone marrow and initiate leukemia., Cell stem cell, 2009, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/19570513