increased hematopoietic stem cell number_Jak2<tm2.1Jlvl>/Jak2<+>,Tg(Vav1-cre)#Cgp/0

http://metadb.riken.jp/0004809I129S2SvPasC57BL6NTacJak2tm21JlvlJak2TgVav1creCgp0Jak2tm21JlvlTgVav1creCgpJak2

increased hematopoietic stem cell number_Jak2<tm2.1Jlvl>/Jak2<+>,Tg(Vav1-cre)#Cgp/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion, Cristin G Print
  http://metadb.riken.jp/db/mgi_rdf/MGI:5527182
• Janus kinase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:96629

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Jak2<tm2.1Jlvl>/Jak2<+>,Tg(Vav1-cre)#Cgp/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Jak2<tm2.1Jlvl>|Tg(Vav1-cre)#Cgp|Jak2<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6NTac

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hematopoietic stem cell number
  http://purl.obolibrary.org/obo/MP_0004809

文献

http://purl.org/net/cito/citesAsAuthority

• Salma. Hasan, et.al., JAK2V617F expression in mice amplifies early hematopoietic cells and gives them a competitive advantage that is hampered by IFNα., Blood, 2013, 122
  http://rdf.ncbi.nlm.nih.gov/pubmed/23863895