increased hematopoietic stem cell number_Runx1<tm3Spe>/Runx1<tm3Spe>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0004809I129S4SvJaeC57BL6CBARunx1tm3SpeRunx1tm3SpeTgMx1cre1Cgn0Runx1tm3SpeTgMx1cre1Cgn

increased hematopoietic stem cell number_Runx1<tm3Spe>/Runx1<tm3Spe>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• runt related transcription factor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:99852
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Runx1<tm3Spe>/Runx1<tm3Spe>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Runx1<tm3Spe>|Tg(Mx1-cre)1Cgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hematopoietic stem cell number
  http://purl.obolibrary.org/obo/MP_0004809

文献

http://purl.org/net/cito/citesAsAuthority

• Jeffrey W. Schindler, et.al., TEL-AML1 corrupts hematopoietic stem cells to persist in the bone marrow and initiate leukemia., Cell stem cell, 2009, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/19570513