increased hematopoietic stem cell number_Ptpmt1<tm2.1Ckq>/Ptpmt1<tm2.1Ckq>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0004809I129S6SvEvTacC57BL6CBASJLPtpmt1tm21CkqPtpmt1tm21CkqTgMx1cre1Cgn0Ptpmt1tm21CkqTgMx1cre1Cgn

increased hematopoietic stem cell number_Ptpmt1<tm2.1Ckq>/Ptpmt1<tm2.1Ckq>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• protein tyrosine phosphatase, mitochondrial 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1913711
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ptpmt1<tm2.1Ckq>/Ptpmt1<tm2.1Ckq>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ptpmt1<tm2.1Ckq>|Tg(Mx1-cre)1Cgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * CBA * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hematopoietic stem cell number
  http://purl.obolibrary.org/obo/MP_0004809

文献

http://purl.org/net/cito/citesAsAuthority

• Wen-Mei. Yu, et.al., Metabolic regulation by the mitochondrial phosphatase PTPMT1 is required for hematopoietic stem cell differentiation., Cell stem cell, 2013, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/23290137