increased hematopoietic stem cell number_Cxcl12<tm1.1Ystz>/Cxcl12<tm1.2Ystz>,Tg(CAG-cre/Esr1*)5Amc/0

http://metadb.riken.jp/0004809I129X1SvJC57BL6CBAFVBNCxcl12tm11YstzCxcl12tm12YstzTgCAGcreEsr15Amc0Cxcl12tm12YstzTgCAGcreEsr15AmcCxcl12tm11Ystz

increased hematopoietic stem cell number_Cxcl12<tm1.1Ystz>/Cxcl12<tm1.2Ystz>,Tg(CAG-cre/Esr1*)5Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 5, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182765
• chemokine (C-X-C motif) ligand 12
  http://metadb.riken.jp/db/mgi_rdf/MGI:103556

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cxcl12<tm1.1Ystz>/Cxcl12<tm1.2Ystz>,Tg(CAG-cre/Esr1*)5Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cxcl12<tm1.2Ystz>|Tg(CAG-cre/Esr1*)5Amc|Cxcl12<tm1.1Ystz>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6 * CBA * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hematopoietic stem cell number
  http://purl.obolibrary.org/obo/MP_0004809

文献

http://purl.org/net/cito/citesAsAuthority

• Yi-Shiuan. Tzeng, et.al., Loss of Cxcl12/Sdf-1 in adult mice decreases the quiescent state of hematopoietic stem/progenitor cells and alters the pattern of hematopoietic regeneration after myelosuppression., Blood, 2011, 117
  http://rdf.ncbi.nlm.nih.gov/pubmed/20833981