decreased hematopoietic stem cell number_Cxcl12<tm1Tng>/Cxcl12<tm1.1Link>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0

http://metadb.riken.jp/0004810I129P2OlaHsdC57BL6CD1FVBNCxcl12tm1TngCxcl12tm11LinkTgSp7tTAtetOEGFPcre1Amc0Cxcl12tm1TngCxcl12tm11LinkTgSp7tTAtetOEGFPcre1Amc

decreased hematopoietic stem cell number_Cxcl12<tm1Tng>/Cxcl12<tm1.1Link>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:3689349
• chemokine (C-X-C motif) ligand 12
  http://metadb.riken.jp/db/mgi_rdf/MGI:103556

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cxcl12<tm1Tng>/Cxcl12<tm1.1Link>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cxcl12<tm1Tng>|Cxcl12<tm1.1Link>|Tg(Sp7-tTA,tetO-EGFP/cre)1Amc

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * CD-1 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased hematopoietic stem cell number
  http://purl.obolibrary.org/obo/MP_0004810

文献

http://purl.org/net/cito/citesAsAuthority

• Adam. Greenbaum, et.al., CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance., Nature, 2013, 495
  http://rdf.ncbi.nlm.nih.gov/pubmed/23434756