abnormal class switch recombination_Aicda<tm1Hon>/Aicda<tm1Hon>,Igh<tm3Mnz>/Igh<tm4.1Mnz>,Trp53bp1<tm1Jc>/Trp53bp1<tm1Jc>

http://metadb.riken.jp/0004816I129C57BL6CBAAicdatm1HonAicdatm1HonIghtm3MnzIghtm41MnzTrp53bp1tm1JcTrp53bp1tm1JcAicdatm1HonIghtm41MnzTrp53bp1tm1JcIghtm3Mnz

abnormal class switch recombination_Aicda<tm1Hon>/Aicda<tm1Hon>,Igh<tm3Mnz>/Igh<tm4.1Mnz>,Trp53bp1<tm1Jc>/Trp53bp1<tm1Jc>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53 binding protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1351320
• activation-induced cytidine deaminase
  http://metadb.riken.jp/db/mgi_rdf/MGI:1342279
• immunoglobulin heavy chain complex
  http://metadb.riken.jp/db/mgi_rdf/MGI:96442

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Aicda<tm1Hon>/Aicda<tm1Hon>,Igh<tm3Mnz>/Igh<tm4.1Mnz>,Trp53bp1<tm1Jc>/Trp53bp1<tm1Jc>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Aicda<tm1Hon>|Igh<tm4.1Mnz>|Trp53bp1<tm1Jc>|Igh<tm3Mnz>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal class switch recombination
  http://purl.obolibrary.org/obo/MP_0004816

文献

http://purl.org/net/cito/citesAsAuthority

• Anne. Bothmer, et.al., 53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination., The Journal of experimental medicine, 2010, 207
  http://rdf.ncbi.nlm.nih.gov/pubmed/20368578