abnormal class switch recombination_Igh<tm2Cgn>/Igh<+>,Igk<tm2Rsky>/Igk<+>,Prkdc<scid>/Prkdc<scid>

http://metadb.riken.jp/0004816I129P2OlaHsdCB17Ightm2CgnIghIgktm2RskyIgkPrkdcscidPrkdcscidPrkdcscidIgktm2RskyIghIgkIghtm2Cgn

abnormal class switch recombination_Igh<tm2Cgn>/Igh<+>,Igk<tm2Rsky>/Igk<+>,Prkdc<scid>/Prkdc<scid>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• immunoglobulin kappa chain complex
  http://metadb.riken.jp/db/mgi_rdf/MGI:96494
• protein kinase, DNA activated, catalytic polypeptide
  http://metadb.riken.jp/db/mgi_rdf/MGI:104779
• immunoglobulin heavy chain complex
  http://metadb.riken.jp/db/mgi_rdf/MGI:96442

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Igh<tm2Cgn>/Igh<+>,Igk<tm2Rsky>/Igk<+>,Prkdc<scid>/Prkdc<scid>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Prkdc<scid>|Igk<tm2Rsky>|Igh<+>|Igk<+>|Igh<tm2Cgn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * CB17

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal class switch recombination
  http://purl.obolibrary.org/obo/MP_0004816

文献

http://purl.org/net/cito/citesAsAuthority

• Elsa. Callén, et.al., Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes., Molecular cell, 2009, 34
  http://rdf.ncbi.nlm.nih.gov/pubmed/19450527