abnormal class switch recombination_Prkar1a<tm2Gsm>/Prkar1a<tm2Gsm>,Tg(Cr2-cre)3Cgn/0

http://metadb.riken.jp/0004816I129X1SvJC57BL6Prkar1atm2GsmPrkar1atm2GsmTgCr2cre3Cgn0TgCr2cre3CgnPrkar1atm2Gsm

abnormal class switch recombination_Prkar1a<tm2Gsm>/Prkar1a<tm2Gsm>,Tg(Cr2-cre)3Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 3, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:3708319
• protein kinase, cAMP dependent regulatory, type I, alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:104878

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Prkar1a<tm2Gsm>/Prkar1a<tm2Gsm>,Tg(Cr2-cre)3Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Cr2-cre)3Cgn|Prkar1a<tm2Gsm>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal class switch recombination
  http://purl.obolibrary.org/obo/MP_0004816

文献

http://purl.org/net/cito/citesAsAuthority

• Bao Q. Vuong, et.al., Specific recruitment of protein kinase A to the immunoglobulin locus regulates class-switch recombination., Nature immunology, 2009, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/19234474