increased endometrial carcinoma incidence_Pgr<tm2(cre)Lyd>/Pgr<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Trp53<tm1Brn>/Trp53<tm1Brn>

http://metadb.riken.jp/0004868I129C57BL6Pgrtm2creLydPgrPtentm1HwuPtentm1HwuTrp53tm1BrnTrp53tm1BrnTrp53tm1BrnPgrtm2creLydPgrPtentm1Hwu

increased endometrial carcinoma incidence_Pgr<tm2(cre)Lyd>/Pgr<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Trp53<tm1Brn>/Trp53<tm1Brn>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• progesterone receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:97567

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pgr<tm2(cre)Lyd>/Pgr<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Trp53<tm1Brn>/Trp53<tm1Brn>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Brn>|Pgr<tm2(cre)Lyd>|Pgr<+>|Pten<tm1Hwu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased endometrial carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0004868

文献

http://purl.org/net/cito/citesAsAuthority

• Takiko. Daikoku, et.al., Conditional loss of uterine Pten unfailingly and rapidly induces endometrial cancer in mice., Cancer research, 2008, 68
  http://rdf.ncbi.nlm.nih.gov/pubmed/18632614