increased endometrial carcinoma incidence_Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Cdh16-cre)91Igr/0

http://metadb.riken.jp/0004868I129P2OlaHsdC57BL6JFVBNICRTrp53tm1BrnTrp53tm1BrnTgCdh16cre91Igr0Trp53tm1BrnTgCdh16cre91Igr

increased endometrial carcinoma incidence_Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Cdh16-cre)91Igr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• transgene insertion 91, Peter Igarashi
  http://metadb.riken.jp/db/mgi_rdf/MGI:2665302

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Cdh16-cre)91Igr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Brn>|Tg(Cdh16-cre)91Igr

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6J * FVB/N * ICR

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased endometrial carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0004868

文献

http://purl.org/net/cito/citesAsAuthority

• Kristian. Ikenberg, et.al., KPNA2 is overexpressed in human and mouse endometrial cancers and promotes cellular proliferation., The Journal of pathology, 2014, 234
  http://rdf.ncbi.nlm.nih.gov/pubmed/24930886
• Peter J. Wild, et.al., p53 suppresses type II endometrial carcinomas in mice and governs endometrial tumour aggressiveness in humans., EMBO molecular medicine, 2012, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/22678923