increased endometrial carcinoma incidence_Pgr<tm2(cre)Lyd>/Pgr<+>,Pten<tm1Hwu>/Pten<tm1Hwu>

http://metadb.riken.jp/0004868I129S1Sv129S4SvJae129X1SvJPgrtm2creLydPgrPtentm1HwuPtentm1HwuPgrPtentm1HwuPgrtm2creLyd

increased endometrial carcinoma incidence_Pgr<tm2(cre)Lyd>/Pgr<+>,Pten<tm1Hwu>/Pten<tm1Hwu>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• progesterone receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:97567
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pgr<tm2(cre)Lyd>/Pgr<+>,Pten<tm1Hwu>/Pten<tm1Hwu>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pgr<+>|Pten<tm1Hwu>|Pgr<tm2(cre)Lyd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased endometrial carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0004868

文献

http://purl.org/net/cito/citesAsAuthority

• T H. Kim, et.al., The synergistic effect of Mig-6 and Pten ablation on endometrial cancer development and progression., Oncogene, 2010, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/20418913
• Tae Hoon. Kim, et.al., Mig-6 suppresses endometrial cancer associated with Pten deficiency and ERK activation., Cancer research, 2014, 74
  http://rdf.ncbi.nlm.nih.gov/pubmed/25377472