increased mean systemic arterial blood pressure_Rgs2<tm1.1Kjb>/Rgs2<tm1.1Kjb>,Tg(Tek-cre/ERT2)1Arnd/?

http://metadb.riken.jp/0004875I129X1SvJC57BL6DBA2Rgs2tm11KjbRgs2tm11KjbTgTekcreERT21ArndRgs2tm11KjbTgTekcreERT21Arnd

increased mean systemic arterial blood pressure_Rgs2<tm1.1Kjb>/Rgs2<tm1.1Kjb>,Tg(Tek-cre/ERT2)1Arnd/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Bernd Arnold
  http://metadb.riken.jp/db/mgi_rdf/MGI:2450326
• regulator of G-protein signaling 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1098271

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rgs2<tm1.1Kjb>/Rgs2<tm1.1Kjb>,Tg(Tek-cre/ERT2)1Arnd/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rgs2<tm1.1Kjb>|Tg(Tek-cre/ERT2)1Arnd

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased mean systemic arterial blood pressure
  http://purl.obolibrary.org/obo/MP_0004875

文献

http://purl.org/net/cito/citesAsAuthority

• Patrick. Osei-Owusu, et.al., Regulator of G protein signaling 2 deficiency causes endothelial dysfunction and impaired endothelium-derived hyperpolarizing factor-mediated relaxation by dysregulating Gi/o signaling., The Journal of biological chemistry, 2012, 287
  http://rdf.ncbi.nlm.nih.gov/pubmed/22354966