increased energy expenditure_Ptpn1<tm2Bbk>/Ptpn1<tm2Bbk>,Ptpn2<tm1.1Ttig>/Ptpn2<tm1.1Ttig>,Tg(Nes-cre)1Kln/0

http://metadb.riken.jp/0004889I129S4SvJaeC57BL6C57BL6JSJLPtpn1tm2BbkPtpn1tm2BbkPtpn2tm11TtigPtpn2tm11TtigTgNescre1Kln0Ptpn2tm11TtigPtpn1tm2BbkTgNescre1Kln

increased energy expenditure_Ptpn1<tm2Bbk>/Ptpn1<tm2Bbk>,Ptpn2<tm1.1Ttig>/Ptpn2<tm1.1Ttig>,Tg(Nes-cre)1Kln/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• protein tyrosine phosphatase, non-receptor type 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97806
• protein tyrosine phosphatase, non-receptor type 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97805
• transgene insertion 1, Rudiger Klein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176172

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ptpn1<tm2Bbk>/Ptpn1<tm2Bbk>,Ptpn2<tm1.1Ttig>/Ptpn2<tm1.1Ttig>,Tg(Nes-cre)1Kln/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ptpn2<tm1.1Ttig>|Ptpn1<tm2Bbk>|Tg(Nes-cre)1Kln

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * C57BL/6J * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased energy expenditure
  http://purl.obolibrary.org/obo/MP_0004889

文献

http://purl.org/net/cito/citesAsAuthority

• Kim. Loh, et.al., Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance., Cell metabolism, 2011, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/22000926