decreased male germ cell number_Amhr2<tm3(cre)Bhr>/Amhr2<+>,Tsc2<tm1.1Mjg>/Tsc2<tm1.1Mjg>

http://metadb.riken.jp/0004901I129S1Sv129S7SvEvBrd129X1SvJC57BL6Amhr2tm3creBhrAmhr2Tsc2tm11MjgTsc2tm11MjgTsc2tm11MjgAmhr2Amhr2tm3creBhr

decreased male germ cell number_Amhr2<tm3(cre)Bhr>/Amhr2<+>,Tsc2<tm1.1Mjg>/Tsc2<tm1.1Mjg>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• tuberous sclerosis 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:102548
• anti-Mullerian hormone type 2 receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:105062

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Amhr2<tm3(cre)Bhr>/Amhr2<+>,Tsc2<tm1.1Mjg>/Tsc2<tm1.1Mjg>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tsc2<tm1.1Mjg>|Amhr2<+>|Amhr2<tm3(cre)Bhr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased male germ cell number
  http://purl.obolibrary.org/obo/MP_0004901

文献

http://purl.org/net/cito/citesAsAuthority

• Pradeep S. Tanwar, et.al., Altered LKB1/AMPK/TSC1/TSC2/mTOR signaling causes disruption of Sertoli cell polarity and spermatogenesis., Human molecular genetics, 2012, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/22791749