abnormal negative T cell selection_Il6st<tm1Thir>/Il6st<tm1Thir>,Tg(TcraH-Y,TcrbH-Y)71Vbo/?

http://metadb.riken.jp/0004918I129C57BL6DBAIl6sttm1ThirIl6sttm1ThirTgTcraHYTcrbHY71VboIl6sttm1ThirTgTcraHYTcrbHY71Vbo

abnormal negative T cell selection_Il6st<tm1Thir>/Il6st<tm1Thir>,Tg(TcraH-Y,TcrbH-Y)71Vbo/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 71, Harald von Boehmer
  http://metadb.riken.jp/db/mgi_rdf/MGI:3044559
• interleukin 6 signal transducer
  http://metadb.riken.jp/db/mgi_rdf/MGI:96560

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Il6st<tm1Thir>/Il6st<tm1Thir>,Tg(TcraH-Y,TcrbH-Y)71Vbo/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Il6st<tm1Thir>|Tg(TcraH-Y,TcrbH-Y)71Vbo

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal negative T cell selection
  http://purl.obolibrary.org/obo/MP_0004918

文献

http://purl.org/net/cito/citesAsAuthority

• Toru. Atsumi, et.al., A point mutation of Tyr-759 in interleukin 6 family cytokine receptor subunit gp130 causes autoimmune arthritis., The Journal of experimental medicine, 2002, 196
  http://rdf.ncbi.nlm.nih.gov/pubmed/12370259