abnormal negative T cell selection_Vav1<tm2Tyb>/Vav1<tm2Tyb>

http://metadb.riken.jp/0004918I129S4SvJae129S8SvEvC57BL10C57BRcdVav1tm2TybVav1tm2TybVav1tm2Tyb

abnormal negative T cell selection_Vav1<tm2Tyb>/Vav1<tm2Tyb>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• vav 1 oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:98923

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Vav1<tm2Tyb>/Vav1<tm2Tyb>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Vav1<tm2Tyb>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * 129S8/SvEv * C57BL/10 * C57BR/cd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal negative T cell selection
  http://purl.obolibrary.org/obo/MP_0004918

文献

http://purl.org/net/cito/citesAsAuthority

• Antonella. Prisco, et.al., Lineage-specific requirement for the PH domain of Vav1 in the activation of CD4+ but not CD8+ T cells., Immunity, 2005, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/16169499