abnormal positive T cell selection_Elk4<tm1Rtr>/Elk4<tm1Rtr>,Tg(TcraH-Y,TcrbH-Y)71Vbo/?

http://metadb.riken.jp/0004919I129SvC57BL6DBA2JElk4tm1RtrElk4tm1RtrTgTcraHYTcrbHY71VboTgTcraHYTcrbHY71VboElk4tm1Rtr

abnormal positive T cell selection_Elk4<tm1Rtr>/Elk4<tm1Rtr>,Tg(TcraH-Y,TcrbH-Y)71Vbo/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 71, Harald von Boehmer
  http://metadb.riken.jp/db/mgi_rdf/MGI:3044559
• ELK4, member of ETS oncogene family
  http://metadb.riken.jp/db/mgi_rdf/MGI:102853

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Elk4<tm1Rtr>/Elk4<tm1Rtr>,Tg(TcraH-Y,TcrbH-Y)71Vbo/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(TcraH-Y,TcrbH-Y)71Vbo|Elk4<tm1Rtr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6 * DBA/2J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal positive T cell selection
  http://purl.obolibrary.org/obo/MP_0004919

文献

http://purl.org/net/cito/citesAsAuthority

• Patrick S. Costello, et.al., Ternary complex factor SAP-1 is required for Erk-mediated thymocyte positive selection., Nature immunology, 2004, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/14770179