abnormal positive T cell selection_Zap70<m1Saka>/Zap70<m1Saka>,Tg(TcraH-Y,TcrbH-Y)71Vbo/0

http://metadb.riken.jp/0004919IBALBcC57BL6JDBA2JZap70m1SakaZap70m1SakaTgTcraHYTcrbHY71Vbo0Zap70m1SakaTgTcraHYTcrbHY71Vbo

abnormal positive T cell selection_Zap70<m1Saka>/Zap70<m1Saka>,Tg(TcraH-Y,TcrbH-Y)71Vbo/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• zeta-chain (TCR) associated protein kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:99613
• transgene insertion 71, Harald von Boehmer
  http://metadb.riken.jp/db/mgi_rdf/MGI:3044559

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Zap70<m1Saka>/Zap70<m1Saka>,Tg(TcraH-Y,TcrbH-Y)71Vbo/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Zap70<m1Saka>|Tg(TcraH-Y,TcrbH-Y)71Vbo

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: BALB/c * C57BL/6J * DBA/2J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal positive T cell selection
  http://purl.obolibrary.org/obo/MP_0004919

文献

http://purl.org/net/cito/citesAsAuthority

• Noriko. Sakaguchi, et.al., Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice., Nature, 2003, 426
  http://rdf.ncbi.nlm.nih.gov/pubmed/14647385