abnormal regulatory T cell physiology_Furin<tm1Jwmc>/Furin<tm1Jwmc>,Tg(Cd4-cre)1Cwi/0

http://metadb.riken.jp/0004946I129P2OlaHsdC57BL6SJLFurintm1JwmcFurintm1JwmcTgCd4cre1Cwi0TgCd4cre1CwiFurintm1Jwmc

abnormal regulatory T cell physiology_Furin<tm1Jwmc>/Furin<tm1Jwmc>,Tg(Cd4-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688
• furin (paired basic amino acid cleaving enzyme)
  http://metadb.riken.jp/db/mgi_rdf/MGI:97513

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Furin<tm1Jwmc>/Furin<tm1Jwmc>,Tg(Cd4-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Cd4-cre)1Cwi|Furin<tm1Jwmc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal regulatory T cell physiology
  http://purl.obolibrary.org/obo/MP_0004946

文献

http://purl.org/net/cito/citesAsAuthority

• Justin P. Edwards, et.al., Regulation of the expression of GARP/latent TGF-β1 complexes on mouse T cells and their role in regulatory T cell and Th17 differentiation., Journal of immunology (Baltimore, Md. : 1950), 2013, 190
  http://rdf.ncbi.nlm.nih.gov/pubmed/23645881