abnormal regulatory T cell physiology_Foxp3<tm1Mal>/Foxp3<tm1Mal>,Lat<tm1Mal>/Lat<tm1Mal>

http://metadb.riken.jp/0004946I129S2SvPasC57BL6Foxp3tm1MalFoxp3tm1MalLattm1MalLattm1MalFoxp3tm1MalLattm1Mal

abnormal regulatory T cell physiology_Foxp3<tm1Mal>/Foxp3<tm1Mal>,Lat<tm1Mal>/Lat<tm1Mal>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• forkhead box P3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1891436
• linker for activation of T cells
  http://metadb.riken.jp/db/mgi_rdf/MGI:1342293

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Foxp3<tm1Mal>/Foxp3<tm1Mal>,Lat<tm1Mal>/Lat<tm1Mal>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Foxp3<tm1Mal>|Lat<tm1Mal>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal regulatory T cell physiology
  http://purl.obolibrary.org/obo/MP_0004946

文献

http://purl.org/net/cito/citesAsAuthority

• Ying. Wang, et.al., Th2 lymphoproliferative disorder of LatY136F mutant mice unfolds independently of TCR-MHC engagement and is insensitive to the action of Foxp3+ regulatory T cells., Journal of immunology (Baltimore, Md. : 1950), 2008, 180
  http://rdf.ncbi.nlm.nih.gov/pubmed/18209052