increased regulatory T cell number_B9d2/Tgfb1<tm1Flv>/Tgfb1<tm2Flv>,Foxp3<tm4(YFP/icre)Ayr>/Foxp3<+>

http://metadb.riken.jp/0004973I129S1Sv129S6SvEvTac129X1SvJB9d2Tgfb1tm1FlvTgfb1tm2FlvFoxp3tm4YFPicreAyrFoxp3Tgfb1tm2FlvFoxp3tm4YFPicreAyrB9d2Tgfb1tm1FlvFoxp3

increased regulatory T cell number_B9d2/Tgfb1<tm1Flv>/Tgfb1<tm2Flv>,Foxp3<tm4(YFP/icre)Ayr>/Foxp3<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transforming growth factor, beta 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:98725
• forkhead box P3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1891436

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• B9d2/Tgfb1<tm1Flv>/Tgfb1<tm2Flv>,Foxp3<tm4(YFP/icre)Ayr>/Foxp3<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tgfb1<tm2Flv>|Foxp3<tm4(YFP/icre)Ayr>|B9d2/Tgfb1<tm1Flv>|Foxp3<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased regulatory T cell number
  http://purl.obolibrary.org/obo/MP_0004973

文献

http://purl.org/net/cito/citesAsAuthority

• Ilona. Gutcher, et.al., Autocrine transforming growth factor-β1 promotes in vivo Th17 cell differentiation., Immunity, 2011, 34
  http://rdf.ncbi.nlm.nih.gov/pubmed/21435587