increased regulatory T cell number_Mtor<tm1.2Koz>/Mtor<tm1.2Koz>,Tg(Cd4-cre)1Cwi/0

http://metadb.riken.jp/0004973I129S4SvJaeC57BL6DBA2Mtortm12KozMtortm12KozTgCd4cre1Cwi0TgCd4cre1CwiMtortm12Koz

increased regulatory T cell number_Mtor<tm1.2Koz>/Mtor<tm1.2Koz>,Tg(Cd4-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• mechanistic target of rapamycin (serine/threonine kinase)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1928394
• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mtor<tm1.2Koz>/Mtor<tm1.2Koz>,Tg(Cd4-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Cd4-cre)1Cwi|Mtor<tm1.2Koz>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased regulatory T cell number
  http://purl.obolibrary.org/obo/MP_0004973

文献

http://purl.org/net/cito/citesAsAuthority

• Greg M. Delgoffe, et.al., The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment., Immunity, 2009, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/19538929