increased regulatory T cell number_Dmd<mdx>/Dmd<mdx>,Spp1<tm1Blh>/Spp1<tm1Blh>

http://metadb.riken.jp/0004973I129S6SvEvTacC57BL6C57BL10C57BL10ScSnDmdmdxDmdmdxSpp1tm1BlhSpp1tm1BlhSpp1tm1BlhDmdmdx

increased regulatory T cell number_Dmd<mdx>/Dmd<mdx>,Spp1<tm1Blh>/Spp1<tm1Blh>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• secreted phosphoprotein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:98389
• dystrophin, muscular dystrophy
  http://metadb.riken.jp/db/mgi_rdf/MGI:94909

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dmd<mdx>/Dmd<mdx>,Spp1<tm1Blh>/Spp1<tm1Blh>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Spp1<tm1Blh>|Dmd<mdx>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * C57BL/10ScSn

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased regulatory T cell number
  http://purl.obolibrary.org/obo/MP_0004973

文献

http://purl.org/net/cito/citesAsAuthority

• Sylvia A. Vetrone, et.al., Osteopontin promotes fibrosis in dystrophic mouse muscle by modulating immune cell subsets and intramuscular TGF-beta., The Journal of clinical investigation, 2009, 119
  http://rdf.ncbi.nlm.nih.gov/pubmed/19451692