increased regulatory T cell number_Foxp3<tm1Flv>/Foxp3<+>,B9d2/Tgfb1<tm1Flv>/Tgfb1<tm2Flv>,Tg(Cd4-cre)1Cwi/?

http://metadb.riken.jp/0004973I129S6SvEvTacC57BL6DBA2Foxp3tm1FlvFoxp3B9d2Tgfb1tm1FlvTgfb1tm2FlvTgCd4cre1CwiB9d2Tgfb1tm1FlvFoxp3tm1FlvFoxp3Tgfb1tm2FlvTgCd4cre1Cwi

increased regulatory T cell number_Foxp3<tm1Flv>/Foxp3<+>,B9d2/Tgfb1<tm1Flv>/Tgfb1<tm2Flv>,Tg(Cd4-cre)1Cwi/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688
• forkhead box P3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1891436
• transforming growth factor, beta 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:98725

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Foxp3<tm1Flv>/Foxp3<+>,B9d2/Tgfb1<tm1Flv>/Tgfb1<tm2Flv>,Tg(Cd4-cre)1Cwi/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• B9d2/Tgfb1<tm1Flv>|Foxp3<tm1Flv>|Foxp3<+>|Tgfb1<tm2Flv>|Tg(Cd4-cre)1Cwi

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased regulatory T cell number
  http://purl.obolibrary.org/obo/MP_0004973

文献

http://purl.org/net/cito/citesAsAuthority

• Ming O. Li, et.al., T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation., Immunity, 2007, 26
  http://rdf.ncbi.nlm.nih.gov/pubmed/17481928