decreased regulatory T cell number_Il2ra<tm1Dw>/Il2ra<tm1Dw>,Tg(Pgk1-HA)1.1Vbo/?,Tg(Tcra/Tcrb)1Vbo/?

http://metadb.riken.jp/0004974CCgIl2ratm1DwTgPgk1HA11VboTgTcraTcrb1VboIl2ratm1DwIl2ratm1DwTgPgk1HA11VboTgTcraTcrb1VboIl2ratm1DwTgPgk1HA11VboTgTcraTcrb1Vbo

decreased regulatory T cell number_Il2ra<tm1Dw>/Il2ra<tm1Dw>,Tg(Pgk1-HA)1.1Vbo/?,Tg(Tcra/Tcrb)1Vbo/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• interleukin 2 receptor, alpha chain
  http://metadb.riken.jp/db/mgi_rdf/MGI:96549
• transgene insertion 1.1, Harald von Boehmer
  http://metadb.riken.jp/db/mgi_rdf/MGI:3759889
• transgene insertion 1, Harald von Boehmer
  http://metadb.riken.jp/db/mgi_rdf/MGI:2680177

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Il2ra<tm1Dw>/Il2ra<tm1Dw>,Tg(Pgk1-HA)1.1Vbo/?,Tg(Tcra/Tcrb)1Vbo/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Il2ra<tm1Dw>|Tg(Pgk1-HA)1.1Vbo|Tg(Tcra/Tcrb)1Vbo

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• C.Cg-Il2ra<tm1Dw> Tg(Pgk1-HA)1.1Vbo Tg(Tcra/Tcrb)1Vbo

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased regulatory T cell number
  http://purl.obolibrary.org/obo/MP_0004974

文献

http://purl.org/net/cito/citesAsAuthority

• Louise M. D'Cruz, et.al., Development and function of agonist-induced CD25+Foxp3+ regulatory T cells in the absence of interleukin 2 signaling., Nature immunology, 2005, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/16227983