decreased regulatory T cell number_Cd28<tm1Huen>/Cd28<tm1Huen>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>

http://metadb.riken.jp/0004974IC57BL6C57BL6NTacCd28tm1HuenCd28tm1HuenGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteCd28tm1HuenGtROSA26Sor

decreased regulatory T cell number_Cd28<tm1Huen>/Cd28<tm1Huen>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• CD28 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88327

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd28<tm1Huen>/Cd28<tm1Huen>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>|Cd28<tm1Huen>|Gt(ROSA)26Sor<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * C57BL/6NTac

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased regulatory T cell number
  http://purl.obolibrary.org/obo/MP_0004974

文献

http://purl.org/net/cito/citesAsAuthority

• Tea. Gogishvili, et.al., Cell-intrinsic and -extrinsic control of Treg-cell homeostasis and function revealed by induced CD28 deletion., European journal of immunology, 2013, 43
  http://rdf.ncbi.nlm.nih.gov/pubmed/23065717