decreased B-1 B cell number_Btk<xid>/?,Tg(IGH-Btk)1Witt/Tg(IGH-Btk)1Witt

http://metadb.riken.jp/0004978IBALBcC3HC57BL6CBANBtkxidTgIGHBtk1WittTgIGHBtk1WittBtkxidTgIGHBtk1Witt

decreased B-1 B cell number_Btk<xid>/?,Tg(IGH-Btk)1Witt/Tg(IGH-Btk)1Witt

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Bruton agammaglobulinemia tyrosine kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:88216
• transgene insertion 1, Owen N Witte
  http://metadb.riken.jp/db/mgi_rdf/MGI:3836558

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Btk<xid>/?,Tg(IGH-Btk)1Witt/Tg(IGH-Btk)1Witt

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Btk<xid>|Tg(IGH-Btk)1Witt

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: BALB/c * C3H * C57BL/6 * CBA/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased B-1 B cell number
  http://purl.obolibrary.org/obo/MP_0004978

文献

http://purl.org/net/cito/citesAsAuthority

• A B. Satterthwaite, et.al., Btk dosage determines sensitivity to B cell antigen receptor cross-linking., Proceedings of the National Academy of Sciences of the United States of America, 1997, 94
  http://rdf.ncbi.nlm.nih.gov/pubmed/9371815