abnormal osteoclast morphology_Slc4a2<tm2Ges>/Slc4a2<tm2Ges>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0004982IC57BL6CBASlc4a2tm2GesSlc4a2tm2GesTgMx1cre1Cgn0Slc4a2tm2GesTgMx1cre1Cgn

abnormal osteoclast morphology_Slc4a2<tm2Ges>/Slc4a2<tm2Ges>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• solute carrier family 4 (anion exchanger), member 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:109351
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Slc4a2<tm2Ges>/Slc4a2<tm2Ges>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Slc4a2<tm2Ges>|Tg(Mx1-cre)1Cgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal osteoclast morphology
  http://purl.obolibrary.org/obo/MP_0004982

文献

http://purl.org/net/cito/citesAsAuthority

• Fabienne. Coury, et.al., SLC4A2-mediated Cl-/HCO3- exchange activity is essential for calpain-dependent regulation of the actin cytoskeleton in osteoclasts., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110
  http://rdf.ncbi.nlm.nih.gov/pubmed/23341620