increased osteoclast cell number_Nos1<tm1Plh>/Nos1<tm1Plh>,Nos2<tm1Mrl>/Nos2<tm1Mrl>,Nos3<tm1Plh>/Nos3<tm1Plh>

http://metadb.riken.jp/0004984I129S4SvJae129S7SvEvBrdNos1tm1PlhNos1tm1PlhNos2tm1MrlNos2tm1MrlNos3tm1PlhNos3tm1PlhNos1tm1PlhNos3tm1PlhNos2tm1Mrl

increased osteoclast cell number_Nos1<tm1Plh>/Nos1<tm1Plh>,Nos2<tm1Mrl>/Nos2<tm1Mrl>,Nos3<tm1Plh>/Nos3<tm1Plh>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• nitric oxide synthase 2, inducible
  http://metadb.riken.jp/db/mgi_rdf/MGI:97361
• nitric oxide synthase 3, endothelial cell
  http://metadb.riken.jp/db/mgi_rdf/MGI:97362
• nitric oxide synthase 1, neuronal
  http://metadb.riken.jp/db/mgi_rdf/MGI:97360

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nos1<tm1Plh>/Nos1<tm1Plh>,Nos2<tm1Mrl>/Nos2<tm1Mrl>,Nos3<tm1Plh>/Nos3<tm1Plh>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nos1<tm1Plh>|Nos3<tm1Plh>|Nos2<tm1Mrl>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * 129S7/SvEvBrd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased osteoclast cell number
  http://purl.obolibrary.org/obo/MP_0004984

文献

http://purl.org/net/cito/citesAsAuthority

• Ken. Sabanai, et.al., Genetic disruption of all NO synthase isoforms enhances BMD and bone turnover in mice in vivo: involvement of the renin-angiotensin system., Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2008, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/18433298