increased osteoclast cell number_Ctsk<tm1Vuo>/Ctsk<tm1Vuo>

http://metadb.riken.jp/0004984I129S7SvEvBrdC57BL6JCtsktm1VuoCtsktm1VuoCtsktm1Vuo

increased osteoclast cell number_Ctsk<tm1Vuo>/Ctsk<tm1Vuo>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cathepsin K
  http://metadb.riken.jp/db/mgi_rdf/MGI:107823

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ctsk<tm1Vuo>/Ctsk<tm1Vuo>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ctsk<tm1Vuo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased osteoclast cell number
  http://purl.obolibrary.org/obo/MP_0004984

文献

http://purl.org/net/cito/citesAsAuthority

• Riku. Kiviranta, et.al., Impaired bone resorption in cathepsin K-deficient mice is partially compensated for by enhanced osteoclastogenesis and increased expression of other proteases via an increased RANKL/OPG ratio., Bone, 2005, 36
  http://rdf.ncbi.nlm.nih.gov/pubmed/15664014