abnormal osteoblast physiology_Smurf1<tm1Yez>/Smurf1<tm1Yez>

http://metadb.riken.jp/0005006EI129S6SvEvTacC57BL6orI129S6SvEvTacNIHBlackSwissSmurf1tm1YezSmurf1tm1YezSmurf1tm1Yez

abnormal osteoblast physiology_Smurf1<tm1Yez>/Smurf1<tm1Yez>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• SMAD specific E3 ubiquitin protein ligase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1923038

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Smurf1<tm1Yez>/Smurf1<tm1Yez>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Smurf1<tm1Yez>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• either: (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * NIH Black Swiss)

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal osteoblast physiology
  http://purl.obolibrary.org/obo/MP_0005006

文献

http://purl.org/net/cito/citesAsAuthority

• Motozo. Yamashita, et.al., Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation., Cell, 2005, 121
  http://rdf.ncbi.nlm.nih.gov/pubmed/15820682